A $100,000 salary in South Carolina takes home about $74,936 a year ($2,882 per biweekly paycheck) after $13,170 federal income tax, $4,244 South Carolina income tax and $7,650 FICA (Social Security and Medicare). Assumes a single filer taking the standard deduction, 2026 federal and South Carolina rates, and no 401(k) or other pre-tax deductions.
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